Nasdaq · IONS · stock

Ionis Pharmaceuticals INC (IONS) stock price history

Every Nasdaq trading session of Ionis Pharmaceuticals INC from May 17, 1991 to Sep 28, 2026: 8,904 daily bars, adjusted for splits and dividends, with minute bars from Jul 13, 2026 forward. The full series is served by the API: a free key covers the last year, paid plans the whole history and minute bars.

IONS adjusted close, 1991 to 2026

IONSIonis Pharmaceuticals INC
$45.57-28.9% over one year
1995200020052010201520202025
$86.50
All time high, 2026
$86.74
52 week high, $43.01 low
8,904
Daily sessions since 1991

Last updated Sep 28, 2026, the last stored session. Refreshes after each trading day. Full 1991 to 2026 series and minute bars.

IONS key facts

  • Ionis Pharmaceuticals INC (IONS) closed at $45.57 on Sep 28, 2026 on Nasdaq.
  • IONS's all time high close is $86.50, set on Feb 6, 2026; its all time low close is $2.80 on Mar 18, 2003.
  • IONS's 52 week range is $43.01 to $86.74.
  • IONS returned -28.9% over the year to Sep 28, 2026 and +32.6% over five years.
  • Over ten years IONS returned +26%, +2.3% a year compounded.
  • IONS's deepest drawdown was -91.7% from Mar 6, 2000 to Mar 18, 2003.
  • DataCedar holds 8,904 daily sessions of IONS history from May 17, 1991 and minute bars from Jul 13, 2026, adjusted for splits and dividends, served by the API under a key.

IONS price chart, 1991 to 2026

IONS adjusted close, May 17, 1991 to Sep 28, 2026$3.25$9.53$27.96$81.991995200020052010201520202025
Adjusted daily close, log scale. 260 sampled points across the full history; the API serves every session.

IONS returns

Price return from the last close on or before the window start to Sep 28, 2026, on adjusted closes.

PeriodReturn
1 month-25.4%
3 months-43.9%
6 months-36.8%
Year to date-42.3%
1 year-28.9%
3 years-1.5%
5 years+32.6%
10 years+25.9%
Since May 17, 1991+355.7%
Compound annual growth, 35.4 years+4.4%

IONS records

Measured on the stored closes; every figure is reproducible from the API series.

All time high close
$86.50 on Feb 6, 2026
All time low close
$2.80 on Mar 18, 2003
52 week high
$86.74 on Feb 5, 2026
52 week low
$43.01 on Sep 23, 2026
Deepest drawdown
-91.7% from Mar 6, 2000 to Mar 18, 2003, recovered Sep 19, 2013
Best single session
+47.7% on Aug 22, 2001
Worst single session
-63.9% on Dec 15, 1999
Volatility, 1 year annualised
44.1%
Sessions closing higher, 1 year
49%
Growth of 1 since 1991
4.6×
Best calendar year
2013, +282%
Worst calendar year
2002, -70%

IONS price history by year

Open is the first session's open, high and low span the year, close is the last session's close, and the return is close over the previous year's close. 1991 starts on May 17, 1991; 2026 runs to Sep 28, 2026.

YearOpenHighLowCloseReturnVolumeSessions
2026$79.88$86.74$43.01$45.57-42.4%489.7M185
2025$35.33$83.61$23.95$79.11+126.3%512.4M250
2024$51.41$54.44$33.33$34.96-30.9%340M252
2023$37.95$52.27$32.69$50.59+33.9%266.8M250
2022$30.73$48.82$28.25$37.77+24.1%266.5M251
2021$56.87$64.37$25.04$30.43-46.2%314M252
2020$60.89$64.34$39.32$56.54-6.4%242M253
2019$53.13$86.58$52.45$60.41+11.7%283.1M252
2018$50.08$59.81$39.07$54.06+7.5%278.2M251
2017$48.02$65.51$37.26$50.30+5.2%355.1M251
2016$61.05$62.68$19.59$47.83-22.8%588.2M252
2015$62.52$77.80$37.38$61.93+0.3%576.4M252
2014$39.79$67.12$22.25$61.74+55.0%581.9M252
2013$10.63$42.69$10.36$39.84+281.6%379.1M252
2012$7.35$15.61$7.02$10.44+44.8%274.3M250
2011$10.20$10.45$6.25$7.21-28.8%168.3M252
2010$11.24$11.82$7.59$10.12-8.9%304.7M252
2009$14.23$18.81$9.77$11.11-21.7%235.9M252
2008$15.85$20.15$9.90$14.18-10.0%382.5M253
2007$11.07$18.23$8.30$15.75+41.6%421.4M251
2006$5.29$14.00$5.09$11.12+112.2%231.3M251
2005$6.00$6.09$2.76$5.24-11.2%97.9M252
2004$6.72$9.90$4.22$5.90-9.2%130.6M252
2003$6.82$8.05$2.50$6.50-1.4%148.6M252
2002$22.38$22.40$6.00$6.59-70.3%160.3M252
2001$10.00$27.15$7.88$22.19+108.8%103.3M248
2000$6.38$39.00$5.75$10.63+70.0%131.1M252
1999$13.25$17.38$3.88$6.25-51.7%72.4M252
1998$12.56$16.25$7.00$12.94+5.1%54M252
1997$18.00$20.75$11.00$12.31-31.6%39.8M253
1996$13.13$24.75$10.38$18.00+37.1%64.5M254
1995$4.00$15.25$3.63$13.13+228.1%41.8M252
1994$6.75$8.38$3.25$4.00-40.7%13.4M252
1993$9.75$11.00$5.50$6.75-30.8%18M253
1992$13.50$17.00$5.00$9.75-29.1%14.9M254
1991$10.75$21.50$8.75$13.75n/a13.6M158

IONS monthly closes, last 12 months

MonthMonth end closeChange
September 2026$45.57-24.5%
August 2026$60.36+16.6%
July 2026$51.77-34.7%
June 2026$79.29+3.6%
May 2026$76.50+2.3%
April 2026$74.76-0.4%
March 2026$75.09-7.5%
February 2026$81.15-1.8%
January 2026$82.67+4.5%
December 2025$79.11-4.4%
November 2025$82.73+11.3%
October 2025$74.30+13.6%

About the IONS data

Daily bars. 8,904 sessions from May 17, 1991 to Sep 28, 2026, one row per Nasdaq trading day with open, high, low, close and volume. Prices are adjusted for splits and cash dividends so the series is comparable across its whole length; the API also serves the raw, split only and dividend only views.

Minute bars. Stored from Jul 13, 2026 forward, most recent session Sep 25, 2026. Minute history is captured from the day collection began and is never backfilled, so this start date is exact. Five minute, fifteen minute and hourly bars are derived from these minutes.

Time and currency. Session dates are Nasdaq trading days; minute timestamps are UTC. Prices are in USD. Volume is shares traded on the session.

Get the data. The REST endpoint returns the daily series as JSON with pagination; a free key serves the last year, Quant and above the full history back to May 17, 1991, and minute bars come with the paid windows. It takes timeframe (1Min, 5Min, 15Min, 1Hour, 1Day), adjustment, start and end. See the bars endpoint and authentication, and pricing for the plan windows.

curl "https://api.datacedar.com/v3/stocks/IONS/bars?timeframe=1Day&adjustment=all&limit=50000" \
  -H "X-API-Key: YOUR_KEY"

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Common questions

IONS share price history

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