Nasdaq · PRME · stock
Prime Medicine, Inc. (PRME) stock price history
Every Nasdaq trading session of Prime Medicine, Inc. from Oct 20, 2022 to Sep 28, 2026: 987 daily bars, adjusted for splits and dividends, with minute bars from Jul 13, 2026 forward. The full series is served by the API: a free key covers the last year, paid plans the whole history and minute bars.
PRME adjusted close, 2022 to 2026
- $21.12
- All time high, 2022
- $6.94
- 52 week high, $2.67 low
- 987
- Daily sessions since 2022
Last updated Sep 28, 2026, the last stored session. Refreshes after each trading day. Full 2022 to 2026 series and minute bars.
PRME key facts
- Prime Medicine, Inc. (PRME) closed at $2.88 on Sep 28, 2026 on Nasdaq.
- PRME's all time high close is $21.12, set on Nov 1, 2022; its all time low close is $1.15 on Apr 8, 2025.
- PRME's 52 week range is $2.67 to $6.94.
- PRME returned -43.8% over the year to Sep 28, 2026.
- Since Oct 20, 2022 PRME returned -81%, -34.7% a year compounded.
- PRME's deepest drawdown was -94.6% from Nov 11, 2022 to Apr 8, 2025.
- DataCedar holds 987 daily sessions of PRME history from Oct 20, 2022 and minute bars from Jul 13, 2026, adjusted for splits and dividends, served by the API under a key.
PRME price chart, 2022 to 2026
PRME returns
Price return from the last close on or before the window start to Sep 28, 2026, on adjusted closes.
| Period | Return |
|---|---|
| 1 month | -20.4% |
| 3 months | -16.2% |
| 6 months | -14.9% |
| Year to date | -16.4% |
| 1 year | -43.8% |
| 3 years | -69.7% |
| 5 years | n/a |
| 10 years | n/a |
| Since Oct 20, 2022 | -81.3% |
| Compound annual growth, 3.9 years | -34.7% |
PRME records
Measured on the stored closes; every figure is reproducible from the API series.
- All time high close
- $21.12 on Nov 1, 2022
- All time low close
- $1.15 on Apr 8, 2025
- 52 week high
- $6.94 on Oct 6, 2025
- 52 week low
- $2.67 on Jun 11, 2026
- Deepest drawdown
- -94.6% from Nov 11, 2022 to Apr 8, 2025, not yet recovered
- Best single session
- +26.2% on May 16, 2025
- Worst single session
- -16.0% on May 19, 2025
- Volatility, 1 year annualised
- 86.5%
- Sessions closing higher, 1 year
- 44%
- Best calendar year
- 2025, +19%
- Worst calendar year
- 2024, -67%
PRME price history by year
Open is the first session's open, high and low span the year, close is the last session's close, and the return is close over the previous year's close. 2022 starts on Oct 20, 2022; 2026 runs to Sep 28, 2026.
| Year | Open | High | Low | Close | Return | Volume | Sessions |
|---|---|---|---|---|---|---|---|
| 2026 | $3.50 | $4.82 | $2.67 | $2.88 | -17.1% | 544.6M | 185 |
| 2025 | $2.93 | $6.94 | $1.11 | $3.47 | +18.8% | 745.8M | 250 |
| 2024 | $8.83 | $9.77 | $2.56 | $2.92 | -67.0% | 255.7M | 252 |
| 2023 | $18.71 | $21.48 | $5.54 | $8.86 | -52.3% | 90.5M | 250 |
| 2022 | $18.97 | $21.73 | $14.52 | $18.58 | n/a | 18M | 50 |
PRME monthly closes, last 12 months
| Month | Month end close | Change |
|---|---|---|
| September 2026 | $2.88 | -19.9% |
| August 2026 | $3.59 | +22.9% |
| July 2026 | $2.92 | -20.9% |
| June 2026 | $3.69 | +3.9% |
| May 2026 | $3.55 | +0.1% |
| April 2026 | $3.55 | +1.9% |
| March 2026 | $3.48 | -24.7% |
| February 2026 | $4.62 | +21.3% |
| January 2026 | $3.81 | +9.8% |
| December 2025 | $3.47 | -9.2% |
| November 2025 | $3.82 | -22.7% |
| October 2025 | $4.94 | -10.8% |
About the PRME data
Daily bars. 987 sessions from Oct 20, 2022 to Sep 28, 2026, one row per Nasdaq trading day with open, high, low, close and volume. Prices are adjusted for splits and cash dividends so the series is comparable across its whole length; the API also serves the raw, split only and dividend only views.
Minute bars. Stored from Jul 13, 2026 forward, most recent session Sep 25, 2026. Minute history is captured from the day collection began and is never backfilled, so this start date is exact. Five minute, fifteen minute and hourly bars are derived from these minutes.
Time and currency. Session dates are Nasdaq trading days; minute timestamps are UTC. Prices are in USD. Volume is shares traded on the session.
Get the data. The REST endpoint returns the daily series as JSON with pagination; a free key serves the last year, Quant and above the full history back to Oct 20, 2022, and minute bars come with the paid windows. It takes timeframe (1Min, 5Min, 15Min, 1Hour, 1Day), adjustment, start and end. See the bars endpoint and authentication, and pricing for the plan windows.
curl "https://api.datacedar.com/v3/stocks/PRME/bars?timeframe=1Day&adjustment=all&limit=50000" \
-H "X-API-Key: YOUR_KEY"Nearby on Nasdaq
Common questions
PRME share price history
