Nasdaq · UPB · stock
Upstream Bio, Inc. (UPB) stock price history
Every Nasdaq trading session of Upstream Bio, Inc. from Oct 11, 2024 to Sep 28, 2026: 491 daily bars, adjusted for splits and dividends, with minute bars from Jul 13, 2026 forward. The full series is served by the API: a free key covers the last year, paid plans the whole history and minute bars.
UPB adjusted close, 2024 to 2026
- $32.60
- All time high, 2026
- $33.68
- 52 week high, $4.99 low
- 491
- Daily sessions since 2024
Last updated Sep 28, 2026, the last stored session. Refreshes after each trading day. Full 2024 to 2026 series and minute bars.
UPB key facts
- Upstream Bio, Inc. (UPB) closed at $5.30 on Sep 28, 2026 on Nasdaq.
- UPB's all time high close is $32.60, set on Jan 13, 2026; its all time low close is $5.17 on Sep 24, 2026.
- UPB's 52 week range is $4.99 to $33.68.
- UPB returned -69.3% over the year to Sep 28, 2026.
- Since Oct 11, 2024 UPB returned -76%, -51.6% a year compounded.
- UPB's deepest drawdown was -84.1% from Jan 13, 2026 to Sep 24, 2026.
- DataCedar holds 491 daily sessions of UPB history from Oct 11, 2024 and minute bars from Jul 13, 2026, adjusted for splits and dividends, served by the API under a key.
UPB price chart, 2024 to 2026
UPB returns
Price return from the last close on or before the window start to Sep 28, 2026, on adjusted closes.
| Period | Return |
|---|---|
| 1 month | -20.8% |
| 3 months | -21.5% |
| 6 months | -38.9% |
| Year to date | -80.6% |
| 1 year | -69.3% |
| 3 years | n/a |
| 5 years | n/a |
| 10 years | n/a |
| Since Oct 11, 2024 | -75.9% |
| Compound annual growth, 2.0 years | -51.6% |
UPB records
Measured on the stored closes; every figure is reproducible from the API series.
- All time high close
- $32.60 on Jan 13, 2026
- All time low close
- $5.17 on Sep 24, 2026
- 52 week high
- $33.68 on Jan 14, 2026
- 52 week low
- $4.99 on Sep 23, 2026
- Deepest drawdown
- -84.1% from Jan 13, 2026 to Sep 24, 2026, not yet recovered
- Best single session
- +18.3% on Sep 2, 2025
- Worst single session
- -47.2% on Feb 11, 2026
- Volatility, 1 year annualised
- 99.9%
- Sessions closing higher, 1 year
- 48%
- Best calendar year
- 2025, +65%
- Worst calendar year
- 2025, +65%
UPB price history by year
Open is the first session's open, high and low span the year, close is the last session's close, and the return is close over the previous year's close. 2024 starts on Oct 11, 2024; 2026 runs to Sep 28, 2026.
| Year | Open | High | Low | Close | Return | Volume | Sessions |
|---|---|---|---|---|---|---|---|
| 2026 | $27.30 | $33.68 | $4.99 | $5.30 | -80.5% | 153.9M | 185 |
| 2025 | $16.46 | $33.00 | $5.14 | $27.15 | +65.1% | 101M | 250 |
| 2024 | $21.50 | $29.46 | $14.97 | $16.44 | n/a | 22.9M | 56 |
UPB monthly closes, last 12 months
| Month | Month end close | Change |
|---|---|---|
| September 2026 | $5.30 | -19.9% |
| August 2026 | $6.62 | +4.9% |
| July 2026 | $6.31 | -8.8% |
| June 2026 | $6.92 | -17.2% |
| May 2026 | $8.36 | -8.9% |
| April 2026 | $9.18 | +2.0% |
| March 2026 | $9.00 | +17.2% |
| February 2026 | $7.68 | -75.3% |
| January 2026 | $31.08 | +14.5% |
| December 2025 | $27.15 | -5.1% |
| November 2025 | $28.60 | +10.6% |
| October 2025 | $25.85 | +37.4% |
About the UPB data
Daily bars. 491 sessions from Oct 11, 2024 to Sep 28, 2026, one row per Nasdaq trading day with open, high, low, close and volume. Prices are adjusted for splits and cash dividends so the series is comparable across its whole length; the API also serves the raw, split only and dividend only views.
Minute bars. Stored from Jul 13, 2026 forward, most recent session Sep 25, 2026. Minute history is captured from the day collection began and is never backfilled, so this start date is exact. Five minute, fifteen minute and hourly bars are derived from these minutes.
Time and currency. Session dates are Nasdaq trading days; minute timestamps are UTC. Prices are in USD. Volume is shares traded on the session.
Get the data. The REST endpoint returns the daily series as JSON with pagination; a free key serves the last year, Quant and above the full history back to Oct 11, 2024, and minute bars come with the paid windows. It takes timeframe (1Min, 5Min, 15Min, 1Hour, 1Day), adjustment, start and end. See the bars endpoint and authentication, and pricing for the plan windows.
curl "https://api.datacedar.com/v3/stocks/UPB/bars?timeframe=1Day&adjustment=all&limit=50000" \
-H "X-API-Key: YOUR_KEY"Nearby on Nasdaq
Common questions
UPB share price history
